Title: Santa María Vacation Packages & Trips 2026 | Expedia.ca [Hotels in Santa María](https://expedia.ca/Santa-Maria-Hotels.d553248634664650762.Travel-Guide-Hotels)[Vacation Rentals in Santa María](https://expedia.ca/Santa-Maria-Vacation-Rentals.d553248634664650762.Travel-Guide-VacationRentals)[Santa María Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Maria.d553248634664650762.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Santa María Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Ready to book your vacation to Santa María? Choose your dates ## Santa María Hotel Deals ![Hotel Saint George](https://images.trvl-media.com/lodging/4000000/3290000/3281500/3281425/260f31f1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Saint George Avenida Cordoba 148 Puerto Iguazú Misiones Fully refundableReserve now, pay when you stay CA $192 CA $202 total Apr 25 - Apr 26 8.8/10 Excellent! (1,008 reviews) The negatives: The WiFi didn’t work during our entire visit and the front desk staff person shrugged his shoulders when I told him I couldn’t connect. We got very inaccurate information about visiting Iguazu falls. The restaurant was closed for renovation which we were not told in advance. The positives: ... Reviewed on Mar 30, 2026 [](https://expedia.ca/Hotel-Search?startDate=25%2F04%2F2026&endDate=26%2F04%2F2026&selected=3281425&PinnedHotelID=3281425&HadPinnedHotel=true®ionId=553248634664650762) ![Gran Melia Iguazú](https://images.trvl-media.com/lodging/1000000/460000/454100/454059/c43a985d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Gran Melia Iguazú Parque Nacional Iguazu Puerto Iguazú Misiones Fully refundableReserve now, pay when you stay CA $1,010 CA $1,022 total Apr 30 - May 1 9.2/10 Wonderful! (1,001 reviews) Amazing place. Reviewed on Mar 28, 2026 [](https://expedia.ca/Hotel-Search?startDate=30%2F04%2F2026&endDate=01%2F05%2F2026&selected=454059&PinnedHotelID=454059&HadPinnedHotel=true®ionId=553248634664650762) ![Loi Suites Iguazú Hotel](https://images.trvl-media.com/lodging/3000000/2460000/2450100/2450070/71380e56_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Loi Suites Iguazú Hotel Selva Iriapu Sin Numero Puerto Iguazú Misiones Fully refundableReserve now, pay when you stay CA $465 CA $477 total May 1 - May 2 9.2/10 Wonderful! (1,000 reviews) Stayed at Loi 2 nights in a superior room. It is difficult to find high end hotels in the Iguazu area unless you stay at the Gran Melia for double or even triple Loi's nightly rates. Do not expect luxury here. While Loi advertises as 5\* it certainly is missing the qualities and details of a high ... Reviewed on Mar 24, 2026 [](https://expedia.ca/Hotel-Search?startDate=01%2F05%2F2026&endDate=02%2F05%2F2026&selected=2450070&PinnedHotelID=2450070&HadPinnedHotel=true®ionId=553248634664650762) [See all 381 properties in Misiones Province](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=01%2F04%2F2026&endDate=02%2F04%2F2026®ionId=6232393) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app